Table 2

Table 2

Newcastle-Ottawa case–control studies | appraisal results

StudySelectionComparability
(can have up to 2 stars)
ExposureRating
Is the case definition adequate? (*)Representativeness of the cases (*)Selection of controls (*)Definition of controlsComparability of cases and controls (**)Ascertainment of exposure (*)Same method of ascertainment for cases and controls (*)Non-response rate (*)
Smith et al9******Poor
Weichenthal et al38*****Poor
Wade et al48*******Good
  • Thresholds for converting the Newcastle-Ottawa scales to Agency for Healthcare Research and Quality standards (good, fair, and poor): Good quality: 3 or 4 stars in Selection domain AND 1 or 2 stars in Comparability domain AND 2 or 3 stars in Exposure domain. Fair quality: 2 stars in Selection domain AND 1 or 2 stars in Comparability domain AND 2 or 3 stars in Exposure domain. Poor quality: 0 or 1 star in Selection domain OR 0 star in Comparability domain OR 0 or 1 star in Exposure domain.