Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury
T Uchida, M Shirasawa, LB Ware, K Kojima… - American journal of …, 2006 - atsjournals.org
Rationale: Receptor for advanced glycation end-products (RAGE) is one of the alveolar type
I cell–associated proteins in the lung. Objectives: To test the hypothesis that RAGE is a …
I cell–associated proteins in the lung. Objectives: To test the hypothesis that RAGE is a …
Activation of the α7 nAChR reduces acid-induced acute lung injury in mice and rats
New evidence indicates that neural mechanisms can down-regulate acute inflammation. In
these studies, we tested the potential role of the α7 nicotinic acetylcholine receptor (α7 …
these studies, we tested the potential role of the α7 nicotinic acetylcholine receptor (α7 …
Thefeasibility, appropriateness, and applicability of trauma scoring systems in low and middle-income countries: a systematic review
I Feldhaus, M Carvalho, G Waiz, J Igu… - Trauma surgery & …, 2020 - tsaco.bmj.com
Background About 5.8 million people die each year as a result of injuries, and nearly 90% of
these deaths occur in low and middle-income countries (LMIC). Trauma scoring is a …
these deaths occur in low and middle-income countries (LMIC). Trauma scoring is a …
COVID-19–associated lung microvascular endotheliopathy: a “from the bench” perspective
J Joffre, L Rodriguez, ZA Matthay, E Lloyd… - American Journal of …, 2022 - atsjournals.org
Rationale: Autopsy and biomarker studies suggest that endotheliopathy contributes to
coronavirus disease (COVID-19)-associated acute respiratory distress syndrome. However …
coronavirus disease (COVID-19)-associated acute respiratory distress syndrome. However …
[HTML][HTML] Specification of implementation interventions to address the cascade of HIV care and treatment in resource-limited settings: a systematic review
Background The global response to HIV has started over 18 million persons on life-saving
antiretroviral therapy (ART)—the vast majority in low-and middle-income countries (LMIC) …
antiretroviral therapy (ART)—the vast majority in low-and middle-income countries (LMIC) …
Postinjury platelet aggregation and venous thromboembolism
ZA Matthay, ZJ Hellmann, B Nunez-Garcia… - Journal of Trauma …, 2022 - journals.lww.com
BACKGROUND Posttraumatic venous thromboembolism (VTE) remains prevalent in
severely injured patients despite chemoprophylaxis. Importantly, although platelets are …
severely injured patients despite chemoprophylaxis. Importantly, although platelets are …
[HTML][HTML] Importance of catecholamine signaling in the development of platelet exhaustion after traumatic injury
ZA Matthay, AT Fields, B Nunez‐Garcia, JJ Park… - Journal of Thrombosis …, 2022 - Elsevier
Background Impaired ex vivo platelet aggregation is common in trauma patients. The
mechanisms driving these impairments remain incompletely understood, but functional …
mechanisms driving these impairments remain incompletely understood, but functional …
Von Willebrand factor as a thrombotic and inflammatory mediator in critical illness
WE Plautz, ZA Matthay, MA Rollins‐Raval… - …, 2020 - Wiley Online Library
The endothelial exocytosis of high‐molecular‐weight multimeric von Willebrand factor (vWF)
may occur in critical illness states, including trauma and sepsis, leading to the sustained …
may occur in critical illness states, including trauma and sepsis, leading to the sustained …
The DISTANCE study: determining the impact of social distancing on trauma epidemiology during the COVID-19 epidemic—an interrupted time-series analysis
ZA Matthay, AE Kornblith, EC Matthay… - Journal of trauma and …, 2021 - journals.lww.com
BACKGROUND The large-scale social distancing efforts to reduce SARS-CoV-2
transmission have dramatically changed human behaviors associated with traumatic …
transmission have dramatically changed human behaviors associated with traumatic …
Outcomes after ultramassive transfusion in the modern era: an Eastern Association for the Surgery of Trauma multicenter study
ZA Matthay, ZJ Hellmann, RA Callcut… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND Despite the widespread institution of modern massive transfusion protocols
with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving …
with balanced blood product ratios, survival for patients with traumatic hemorrhage receiving …