Chronic rhinosinusitis with nasal polyps

WW Stevens, RP Schleimer, RC Kern - The journal of allergy and clinical …, 2016 - Elsevier
Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed
by the presence of both subjective and objective evidence of chronic sinonasal …

The etiology and pathogenesis of chronic rhinosinusitis: a review of current hypotheses

K Lam, R Schleimer, RC Kern - Current allergy and asthma reports, 2015 - Springer
Chronic rhinosinusitis (CRS) is a broad clinical syndrome that is characterized by prolonged
mucosal inflammation of the nose and paranasal sinuses, and is typically divided into two …

Perspectives on the etiology of chronic rhinosinusitis: an immune barrier hypothesis

RC Kern, DB Conley, W Walsh… - American journal of …, 2008 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) has been defined as persistent symptomatic
inflammation of the nasal and sinus mucosa resulting from the interaction of multiple host …

Cytokines in chronic rhinosinusitis. Role in eosinophilia and aspirin-exacerbated respiratory disease

WW Stevens, CJ Ocampo, S Berdnikovs… - American journal of …, 2015 - atsjournals.org
Rationale: The mechanisms that underlie the pathogenesis of chronic rhinosinusitis without
nasal polyps (CRSsNP), chronic rhinosinusitis with nasal polyps (CRSwNP), and aspirin …

Associations between inflammatory endotypes and clinical presentations in chronic rhinosinusitis

WW Stevens, AT Peters, BK Tan, AI Klingler… - The Journal of Allergy …, 2019 - Elsevier
Background Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by
mucosal inflammation in the nose and paranasal sinuses. Inflammation in CRS is also …

Candidate's thesis: chronic sinusitis and anosmia: pathologic changes in the olfactory mucosa

RC Kern - The Laryngoscope, 2000 - Wiley Online Library
Objectives To evaluate histological changes in the olfactory mucosa of patients with chronic
rhinosinusitis. These results are analyzed in light of current understanding of the …

Incidence and associated premorbid diagnoses of patients with chronic rhinosinusitis

BK Tan, RK Chandra, J Pollak, A Kato… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: Chronic rhinosinusitis (CRS) is a prevalent condition with underexplored
risk factors. OBJECTIVES: We sought to determine CRS incidence and evaluate …

Relationships between severity of chronic rhinosinusitis and nasal polyposis, asthma, and atopy

AN Pearlman, RK Chandra, D Chang… - American journal of …, 2009 - journals.sagepub.com
Background The effect of comorbid conditions such as asthma and atopy on the severity of
chronic rhinosinusitis (CRS) and the presence of nasal polyps (NPs) remains an area of …

Association between severity of asthma and degree of chronic rhinosinusitis

DC Lin, RK Chandra, BK Tan, W Zirkle… - American journal of …, 2011 - journals.sagepub.com
Background There is a clinical association between asthma and chronic rhinosinusitis
(CRS). This study was designed to determine whether severity of coexistent asthma affects …

Nasal and sinus symptoms and chronic rhinosinusitis in a population‐based sample

AG Hirsch, WF Stewart, AS Sundaresan, AJ Young… - Allergy, 2017 - Wiley Online Library
Background The objective of this study was to describe the first US‐based study to use the
European Position Paper on Rhinosinusitis (EPOS) criteria to study the prevalence of …