The scope and purpose of this work is 2-fold: to synthesize the available evidence and to
translate it into recommendations. This document provides recommendations only when …

Any opinions, findings, and conclusions or recommendations expressed in this material are
those of the authors and do not necessarily reflect the views of the US Army Contracting …

The purpose of this work is to identify and synthesize research produced since the second
edition of these Guidelines was published and incorporate new results into revised evidence …

Importance Understanding the major health problems in the United States and how they are
changing over time is critical for informing national health policy. Objectives To measure the …

Background The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used
the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk …

Although anaesthesiologists strive to avoid hypoxaemia during surgery, reliably predicting
future intraoperative hypoxaemia is not possible at present. Here, we report the …

When the fourth edition of the Brain Trauma Foundation's Guidelines for the Management of
Severe Traumatic Brain Injury were finalized in late 2016, it was known that the results of the …

Objectives: To produce a treatment algorithm for the ICU management of infants, children,
and adolescents with severe traumatic brain injury. Data Sources: Studies included in the …

OBJECTIVE: To examine disability in children and adolescents after traumatic brain injury
(TBI) across the spectrum of injury severity. METHODS: This was a prospective cohort study …

Traumatic brain injury is a global health concern and is the leading cause of traumatic
morbidity and mortality in children. Despite a lower overall mortality than in adult traumatic …