Bioactive sphingolipids including ceramides are involved in a variety of pathophysiological
processes by regulating cell death and survival. The objective of the current study was to …

Preeclampsia (PE), an hypertensive disorder of pregnancy, exhibits increased circulating
levels of a short form of the auxillary TGF-beta (TGFB) receptor endoglin (sENG). Until now …

Autophagy is the catabolic degradation of cellular cytoplasmic constituents via the lysosomal
pathway that physiologically elicits a primarily cytoprotective function, but can rapidly be …

Aberrant ceramide build-up in preeclampsia, a serious disorder of pregnancy, causes
exuberant autophagy-mediated trophoblast cell death. The significance of ceramide …

Background We evaluated the impact of socioeconomic status on presentation,
management, and outcomes of ventral hernias. Methods The Abdominal Core Health …

Ventral hernia repair remains one of the most common procedures performed by surgeons
and more than 600,000 ventral hernias are repaired annually in the United States. 1–3 All …

Trophoblast cell fusion is a prerequisite for proper human placental development. Herein we
examined the contribution of Par6 (Partitioning defective protein 6), a key regulator of cell …

Background Morbid obesity, with a body mass index 35 kg/m 2, is a commonly used cutoff
for denying elective transversus abdominis release. Although obesity is linked to short-term …

Introduction The most appropriate method of reconstructing the abdominal wall at the site of
a simultaneous stoma takedown is controversial. The contaminated field, concomitant GI …

Introduction The optimal pain management strategy after open ventral hernia repair (VHR)
with transversus abdominus release (TAR) is unknown. Opioids are known to have an …