Introduction Acute kidney injury (AKI) can evolve quickly and clinical measures of function
often fail to detect AKI at a time when interventions are likely to provide benefit. Identifying …

Rationale: We recently reported two novel biomarkers for acute kidney injury (AKI), tissue
inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein 7 …

Importance Antibiotic-resistant bacteria are associated with increased patient morbidity and
mortality. It is unknown whether wearing gloves and gowns for all patient contact in the …

Islet duodenal homeobox 1 (IDX-1/PF-1/STF-1/PDX-1), a homeodomain protein that
transactivates the insulin promoter, has been shown by targeted gene ablation to be …

Abstract Early Warning Scores (EWS) are a composite evaluation of a patient's basic
physiology, changes of which are the first indicators of clinical decline and are used to …

Purpose The aim of the RUBY study was to evaluate novel candidate biomarkers to enable
prediction of persistence of renal dysfunction as well as further understand potential …

Failure to rescue in the surgical patient: a review : Current Opinion in Critical Care Failure to
rescue in the surgical patient: a review : Current Opinion in Critical Care Log in or Register …

BACKGROUND Acute kidney injury (AKI) is an important complication in surgical patients.
Existing biomarkers and clinical prediction models underestimate the risk for developing …

Methods: Critically ill uninfected SIRS patients were followed longitudinally for the
development of sepsis. All patients had whole blood collected daily for gene expression …

Purpose: While fever may be a presenting symptom of COVID-19, fever at hospital
admission has not been identified as a predictor of mortality. However, hyperthermia during …