Western Trauma Association critical decisions in trauma: penetrating neck trauma

JL Sperry, EE Moore, R Coimbra, M Croce… - Journal of Trauma …, 2013 - journals.lww.com
This is a recommended algorithm of the Western Trauma Association for the management of
penetrating neck trauma that has penetrated the platysma muscle of the neck. Because of …

[HTML][HTML] Prehospital plasma during air medical transport in trauma patients at risk for hemorrhagic shock

JL Sperry, FX Guyette, JB Brown… - … England Journal of …, 2018 - Mass Medical Soc
Background After a person has been injured, prehospital administration of plasma in
addition to the initiation of standard resuscitation procedures in the prehospital environment …

An FFP: PRBC transfusion ratio≥ 1: 1.5 is associated with a lower risk of mortality after massive transfusion

JL Sperry, JB Ochoa, SR Gunn… - Journal of Trauma …, 2008 - journals.lww.com
Objective: The detrimental effects of coagulopathy, hypothermia, and acidosis are well
described as markers for mortality after traumatic hemorrhage. Recent military experience …

Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome

GA Watson, JL Sperry, MR Rosengart… - Journal of Trauma …, 2009 - journals.lww.com
Background: Blood transfusion is known to be an independent risk factor for mortality,
multiple organ failure (MOF), acute respiratory distress syndrome (ARDS), and nosocomial …

[HTML][HTML] Platelet-derived HMGB1 is a critical mediator of thrombosis

S Vogel, R Bodenstein, Q Chen, S Feil… - The Journal of …, 2015 - Am Soc Clin Investig
Thrombosis and inflammation are intricately linked in several major clinical disorders,
including disseminated intravascular coagulation and acute ischemic events. The damage …

Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury: a double-blind, placebo-controlled, randomized clinical trial

FX Guyette, JB Brown, MS Zenati, BJ Early-Young… - JAMA …, 2021 - jamanetwork.com
Importance In-hospital administration of tranexamic acid after injury improves outcomes in
patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic …

Early use of vasopressors after injury: caution before constriction

JL Sperry, JP Minei, HL Frankel, MA West… - Journal of Trauma …, 2008 - journals.lww.com
Objective: Recent evidence suggests that overly aggressive crystalloid resuscitation is
associated with poor outcome. This has led to a renewed interest in the use of vasopressors …

Association of prehospital plasma transfusion with survival in trauma patients with hemorrhagic shock when transport times are longer than 20 minutes: a post hoc …

AE Pusateri, EE Moore, HB Moore, TD Le… - JAMA …, 2020 - jamanetwork.com
Importance Both military and civilian clinical practice guidelines include early plasma
transfusion to achieve a plasma to red cell ratio approaching 1: 1 to 1: 2. However, it was not …

[HTML][HTML] Updated guidelines to reduce venous thromboembolism in trauma patients: a Western Trauma Association critical decisions algorithm

EJ Ley, CVR Brown, EE Moore, JA Sava… - Journal of trauma and …, 2020 - journals.lww.com
This is a recommended evaluation and management algorithm from the Western Trauma
Association (WTA) Algorithms Committee focused on the management of pharmacologic …

Temporal trends of postinjury multiple-organ failure: still resource intensive, morbid, and lethal

A Sauaia, EE Moore, JL Johnson, TL Chin… - Journal of Trauma …, 2014 - journals.lww.com
BACKGROUND While the incidence of postinjury multiple-organ failure (MOF) has declined
during the past decade, temporal trends of its morbidity, mortality, presentation patterns, and …