Western Trauma Association critical decisions in trauma: penetrating neck trauma
This is a recommended algorithm of the Western Trauma Association for the management of
penetrating neck trauma that has penetrated the platysma muscle of the neck. Because of …
penetrating neck trauma that has penetrated the platysma muscle of the neck. Because of …
[HTML][HTML] Prehospital plasma during air medical transport in trauma patients at risk for hemorrhagic shock
Background After a person has been injured, prehospital administration of plasma in
addition to the initiation of standard resuscitation procedures in the prehospital environment …
addition to the initiation of standard resuscitation procedures in the prehospital environment …
An FFP: PRBC transfusion ratio≥ 1: 1.5 is associated with a lower risk of mortality after massive transfusion
Objective: The detrimental effects of coagulopathy, hypothermia, and acidosis are well
described as markers for mortality after traumatic hemorrhage. Recent military experience …
described as markers for mortality after traumatic hemorrhage. Recent military experience …
Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome
GA Watson, JL Sperry, MR Rosengart… - Journal of Trauma …, 2009 - journals.lww.com
Background: Blood transfusion is known to be an independent risk factor for mortality,
multiple organ failure (MOF), acute respiratory distress syndrome (ARDS), and nosocomial …
multiple organ failure (MOF), acute respiratory distress syndrome (ARDS), and nosocomial …
[HTML][HTML] Platelet-derived HMGB1 is a critical mediator of thrombosis
Thrombosis and inflammation are intricately linked in several major clinical disorders,
including disseminated intravascular coagulation and acute ischemic events. The damage …
including disseminated intravascular coagulation and acute ischemic events. The damage …
Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury: a double-blind, placebo-controlled, randomized clinical trial
FX Guyette, JB Brown, MS Zenati, BJ Early-Young… - JAMA …, 2021 - jamanetwork.com
Importance In-hospital administration of tranexamic acid after injury improves outcomes in
patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic …
patients at risk for hemorrhage. Data demonstrating the benefit and safety of the pragmatic …
Early use of vasopressors after injury: caution before constriction
Objective: Recent evidence suggests that overly aggressive crystalloid resuscitation is
associated with poor outcome. This has led to a renewed interest in the use of vasopressors …
associated with poor outcome. This has led to a renewed interest in the use of vasopressors …
Association of prehospital plasma transfusion with survival in trauma patients with hemorrhagic shock when transport times are longer than 20 minutes: a post hoc …
Importance Both military and civilian clinical practice guidelines include early plasma
transfusion to achieve a plasma to red cell ratio approaching 1: 1 to 1: 2. However, it was not …
transfusion to achieve a plasma to red cell ratio approaching 1: 1 to 1: 2. However, it was not …
[HTML][HTML] Updated guidelines to reduce venous thromboembolism in trauma patients: a Western Trauma Association critical decisions algorithm
This is a recommended evaluation and management algorithm from the Western Trauma
Association (WTA) Algorithms Committee focused on the management of pharmacologic …
Association (WTA) Algorithms Committee focused on the management of pharmacologic …
Temporal trends of postinjury multiple-organ failure: still resource intensive, morbid, and lethal
A Sauaia, EE Moore, JL Johnson, TL Chin… - Journal of Trauma …, 2014 - journals.lww.com
BACKGROUND While the incidence of postinjury multiple-organ failure (MOF) has declined
during the past decade, temporal trends of its morbidity, mortality, presentation patterns, and …
during the past decade, temporal trends of its morbidity, mortality, presentation patterns, and …