Cellular Ca 2+ signals are crucial in the control of most physiological processes, cell
injuryand programmed cell death; mitochondria play a pivotal role in the regulation of such …

The design and engineering of organic fluorescent Ca2+ indicators approximately 30 years
ago opened the door for imaging cellular Ca2+ signals with a high degree of temporal and …

Vasopressin and oxytocin are made and released by neurons of the hypothalamo-
neurohypophysial system. Pulse labeling these neurons with radioactive amino acid …

Seven mouse monoclonal antibodies (IgGs) were produced against rat neurophysins (NPs).
Three were specifically directed against vasopressin-associated NP (NP-AVP), and four …

We observed a severe autosomal recessive movement disorder in mice used within our
laboratory. We pursued a series of experiments to define the genetic lesion underlying this …

It is becoming increasingly clear that mitochondrial Ca2+ uptake from and release into the
cytosol has important consequences for neuronal and glial activity. Ca2+ regulates …

Zn2+ is coreleased with glutamate from mossy fiber terminals and can influence synaptic
function. Here, we demonstrate that synaptically released Zn2+ activates a selective …

Abstract Inositol 1, 4, 5‐trisphosphate receptors (IP3R) are mediators of second messenger‐
induced intracellular calcium release. Three isoforms are known to be expressed in brain …

The voltage‐dependent potassium channel subunit Kv2. 1 is widely expressed throughout
the mammalian CNS and is clustered primarily on the somata and proximal dendrites, but …

The spatiotemporal evolution of cerebral microcirculatory adjustments to functional brain
stimulation is the fundamental determinant of the functional specificity of hemodynamically …