Preperitoneal pelvic packing reduces mortality in patients with life-threatening hemorrhage due to unstable pelvic fractures

CC Burlew, EE Moore, PF Stahel… - Journal of Trauma …, 2017 - journals.lww.com
BACKGROUND A 2015 American Association for the Surgery of Trauma trial reported a
32% mortality for pelvic fracture patients in shock. Angioembolization (AE) is the most …

Beta-blocker use is associated with improved outcomes in adult trauma patients

S Arbabi, EM Campion, MR Hemmila… - Journal of Trauma …, 2007 - journals.lww.com
Background: Beta-adrenoreceptor blocker (β-blocker) therapy may improve outcomes in
surgical patients by decreasing cardiac oxygen consumption and hypermetabolism …

Expanded screening criteria for blunt cerebrovascular injury: a bigger impact than anticipated

AE Geddes, CC Burlew, AE Wagenaar, WL Biffl… - The American Journal of …, 2016 - Elsevier
Background We implemented expanded screening criteria for blunt cerebrovascular injuries
(BCVIs) in an attempt to capture the remaining 20% of patients not historically identified with …

Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury

BM Howard, LZ Kornblith, SA Christie… - Trauma surgery & …, 2017 - tsaco.bmj.com
Background Recent studies have demonstrated the vital influence of commensal microbial
communities on human health. The central role of the gut in the response to injury is well …

Timing and volume of crystalloid and blood products in pediatric trauma: an Eastern Association for the Surgery of Trauma multicenter prospective observational study

SF Polites, S Moody, RF Williams… - Journal of Trauma …, 2020 - journals.lww.com
BACKGROUND The purpose of this study was to determine the relationship between timing
and volume of crystalloid before blood products and mortality, hypothesizing that earlier …

Preinjury alcohol exposure attenuates the neuroinflammatory response to traumatic brain injury

MD Goodman, AT Makley, EM Campion… - Journal of Surgical …, 2013 - Elsevier
Background Traumatic brain injury (TBI) initiates a neuroinflammatory response that
increases the risk of TBI-related mortality. Acute alcohol intoxication at the time of TBI is …

Preperitoneal pelvic packing is effective for hemorrhage control in open pelvic fractures

EE Moskowitz, CC Burlew, EE Moore… - The American Journal of …, 2018 - Elsevier
Background Open pelvic fractures are life-threatening injuries. Preperitoneal pelvic packing
(PPP) has been suggested to be ineffective for hemorrhage control in open pelvic fractures …

To shunt or not to shunt in combined orthopedic and vascular extremity trauma

JR Wlodarczyk, AS Thomas, R Schroll… - Journal of Trauma …, 2018 - journals.lww.com
BACKGROUND There exists a long established but not validated practice of placing
temporary intravascular shunts (TIVS) in cases of combined vascular and orthopedic …

Inflate and pack! Pelvic packing combined with REBOA deployment prevents hemorrhage related deaths in unstable pelvic fractures

NL Werner, EE Moore, M Hoehn, R Lawless… - Injury, 2022 - Elsevier
Introduction Resuscitative endovascular balloon occlusion of the aorta (REBOA) is
advocated for hemorrhage control in pelvic fracture patients in shock. We evaluated REBOA …

Resuscitation with washed aged packed red blood cell units decreases the proinflammatory response in mice after hemorrhage

RM Belizaire, AT Makley, EM Campion… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND Resuscitation with blood products instead of crystalloid in the treatment of
hemorrhagic shock has been associated with improved outcomes in trauma patients …