Stress, epigenetics and depression: a systematic review

C Park, JD Rosenblat, E Brietzke, Z Pan, Y Lee… - Neuroscience & …, 2019 - Elsevier
Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …

Respiratory syncytial virus hospitalization and mortality: systematic review and meta‐analysis

RT Stein, LJ Bont, H Zar, FP Polack, C Park… - Pediatric …, 2017 - Wiley Online Library
Background: Respiratory syncytial virus (RSV) is a major public health burden worldwide.
We aimed to review the current literature on the incidence and mortality of severe RSV in …

The effect of loneliness on distinct health outcomes: a comprehensive review and meta-analysis

C Park, A Majeed, H Gill, J Tamura, RC Ho… - Psychiatry …, 2020 - Elsevier
The primary objective was to evaluate the comparative effects of loneliness on multiple
distinct health outcomes. The literature was qualitatively reviewed to identify loneliness risk …

[HTML][HTML] Deep learning-enabled coronary CT angiography for plaque and stenosis quantification and cardiac risk prediction: an international multicentre study

A Lin, N Manral, P McElhinney, A Killekar… - The Lancet Digital …, 2022 - thelancet.com
Background Atherosclerotic plaque quantification from coronary CT angiography (CCTA)
enables accurate assessment of coronary artery disease burden and prognosis. We sought …

Applications of machine learning algorithms to predict therapeutic outcomes in depression: a meta-analysis and systematic review

Y Lee, RM Ragguett, RB Mansur, JJ Boutilier… - Journal of affective …, 2018 - Elsevier
Background No previous study has comprehensively reviewed the application of machine
learning algorithms in mood disorders populations. Herein, we qualitatively and …

[HTML][HTML] Recognition and treatment of cognitive dysfunction in major depressive disorder

H Zuckerman, Z Pan, C Park, E Brietzke… - Frontiers in …, 2018 - frontiersin.org
Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional
mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic …

[HTML][HTML] Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

C Park, Y Suh, AM Cuervo - Nature communications, 2015 - nature.com
Chaperone-mediated autophagy (CMA) is activated in response to cellular stressors to
prevent cellular proteotoxicity through selective degradation of altered proteins in …

Cognitive impairment in major depressive disorder

Z Pan, C Park, E Brietzke, H Zuckerman, C Rong… - CNS …, 2019 - cambridge.org
Cognitive dysfunction is a symptomatic domain identified across many mental disorders.
Cognitive deficits in individuals with major depressive disorder (MDD) contribute …

Glomus tumors in neurofibromatosis type 1: genetic, functional, and clinical evidence of a novel association

H Brems, C Park, O Maertens, A Pemov, L Messiaen… - Cancer research, 2009 - AACR
Abstract Neurofibromatosis type 1 (NF1) is a common disorder that arises secondary to
mutations in the tumor suppressor gene NF1. Glomus tumors are small, benign but painful …

Pharmacological interventions targeting anhedonia in patients with major depressive disorder: a systematic review

B Cao, J Zhu, H Zuckerman, JD Rosenblat… - Progress in Neuro …, 2019 - Elsevier
Anhedonia is defined as a diminished ability to experience interest or pleasure, and is a
critical psychopathological dimension of major depressive disorder (MDD). The purpose of …