User profiles for "author:Atsushi Kawaguchi"

Kawaguchi Atsushi

- Verified email at cc.saga-u.ac.jp - Cited by 8837

ATSUSHI KAWAGUCHI

- Verified email at marianna-u.ac.jp - Cited by 662

[HTML][HTML] The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)

M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Sentinel lymph node biopsy using indocyanine green fluorescence in early-stage breast cancer: a meta-analysis

T Sugie, T Ikeda, A Kawaguchi, A Shimizu… - International journal of …, 2017 - Springer
Sentinel lymph node (SLN) biopsy using indocyanine green (ICG) fluorescence is safe and
has a high detection rate for SLNs. However, the results of this novel technique are …

Periostin: an emerging biomarker for allergic diseases

K Izuhara, S Nunomura, Y Nanri, J Ono, M Takai… - Allergy, 2019 - Wiley Online Library
Periostin is a matricellular protein as well as an extracellular matrix (ECM) protein belonging
to the fasciclin family. Periostin plays important roles as a matricellular protein in the setting …

[PDF][PDF] Safety and antitumor activity of anti–PD-1 antibody, nivolumab, in patients with platinum-resistant ovarian cancer

J Hamanishi, M Mandai, T Ikeda, M Minami… - Journal of Clinical …, 2015 - researchmap.jp
Purpose Programmed death-1 (PD-1), a coinhibitory immune signal receptor expressed in T
cells, binds to PD-1 ligand and regulates antitumor immunity. Nivolumab is an anti–PD-1 …

[PDF][PDF] Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli

K Imamura, N Imamachi, G Akizuki, M Kumakura… - Molecular cell, 2014 - cell.com
Although thousands of long noncoding RNAs (lncRNAs) are localized in the nucleus, only a
few dozen have been functionally characterized. Here we show that nuclear enriched …

[PDF][PDF] Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice

K Tomita, T Teratani, T Suzuki, M Shimizu, H Sato… - …, 2014 - Wiley Online Library
Although nonalcoholic steatohepatitis (NASH) is associated with hypercholesterolemia, the
underlying mechanisms of this association have not been clarified. We aimed to elucidate …

The structural basis for an essential subunit interaction in influenza virus RNA polymerase

E Obayashi, H Yoshida, F Kawai, N Shibayama… - Nature, 2008 - nature.com
Influenza A virus is a major human and animal pathogen with the potential to cause
catastrophic loss of life. The virus reproduces rapidly, mutates frequently and occasionally …

Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunits

T Naito, F Momose, A Kawaguchi, K Nagata - Journal of virology, 2007 - Am Soc Microbiol
Transcription and replication of the influenza virus RNA genome occur in the nuclei of
infected cells through the viral RNA-dependent RNA polymerase consisting of PB1, PB2 …

MAFLD better predicts the progression of atherosclerotic cardiovascular risk than NAFLD: generalized estimating equation approach

T Tsutsumi, M Eslam, T Kawaguchi… - Hepatology …, 2021 - Wiley Online Library
Aim Metabolic associated fatty liver disease (MAFLD) partly overlaps with non‐alcoholic fatty
liver disease (NAFLD). Thus, using a generalized estimating equation (GEE) approach, we …

3CL protease inhibitors with an electrophilic arylketone moiety as anti-SARS-CoV-2 agents

S Konno, K Kobayashi, M Senda, Y Funai… - Journal of Medicinal …, 2021 - ACS Publications
The novel coronavirus, SARS-CoV-2, has been identified as the causative agent for the
current coronavirus disease (COVID-19) pandemic. 3CL protease (3CLpro) plays a pivotal …