Delirium in critically ill patients

Peter Jackson; Akram Khan

doi:10.1016/j.ccc.2015.03.011

Delirium in critically ill patients

Crit Care Clin. 2015 Jul;31(3):589-603. doi: 10.1016/j.ccc.2015.03.011. Epub 2015 May 4.

Authors

Peter Jackson¹, Akram Khan²

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.
² Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, School of Medicine, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, UHN67, Portland, OR 97239-3098, USA. Electronic address: khana@ohsu.edu.

PMID: 26118922
DOI: 10.1016/j.ccc.2015.03.011

Abstract

Delirium in the intensive care unit (ICU) is a common diagnosis, with an incidence ranging between 45% and 87%. Delirium represents a significant burden both to the patient and to the health care system, with a 3.2-fold increase in 6-month mortality and annual US health care costs up to $16 billion. In this review, the diagnosis, epidemiology, and risk factors for delirium in the ICU are discussed. The pathophysiology of delirium and evolving prevention and treatment modalities are outlined.

Keywords: Critically ill; Delirium; Encephelopathy; Intensive care unit.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Critical Illness*
Delirium* / classification
Delirium* / epidemiology
Delirium* / therapy
Humans
Intensive Care Units
Risk Factors

Abstract

Publication types

MeSH terms

Grants and funding