Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study

Burns. 2004 Dec;30(8):851-3. doi: 10.1016/j.burns.2004.05.009.

Abstract

We describe the use of gabapentin for the treatment of itching in wound healing in 35 children. All children were already treated with chlorpheniramine and trimeprazine but they remained irritable and were constantly rubbing their wounds. Within 24h of commencing treatment itching had improved significantly in all of the children.

MeSH terms

  • Adolescent
  • Amines / adverse effects
  • Amines / therapeutic use*
  • Antipruritics / adverse effects
  • Antipruritics / therapeutic use*
  • Burns / complications*
  • Burns / physiopathology
  • Child
  • Child Behavior Disorders / chemically induced
  • Child, Preschool
  • Cyclohexanecarboxylic Acids / adverse effects
  • Cyclohexanecarboxylic Acids / therapeutic use*
  • Gabapentin
  • Humans
  • Infant
  • Male
  • Pruritus / drug therapy*
  • Pruritus / etiology
  • Wound Healing / physiology
  • gamma-Aminobutyric Acid / adverse effects
  • gamma-Aminobutyric Acid / therapeutic use*

Substances

  • Amines
  • Antipruritics
  • Cyclohexanecarboxylic Acids
  • gamma-Aminobutyric Acid
  • Gabapentin