Original contributionEffect of crystalloid infusion on hematocrit and intravascular volume in healthy, nonbleeding subjects
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Cited by (48)
Measurement of Blood Loss in Cardiac Surgery: Still Too Much
2018, Annals of Thoracic SurgeryFluid Composition and Clinical Effects
2015, Critical Care ClinicsCitation Excerpt :After infusion, it is rapidly distributed between the compartments of the extracellular space. In health, approximately 60% of the infused volume diffuses from the intravascular space into the interstitial compartment within 20 minutes of administration.8 These fluid shifts are even faster in conditions associated with endothelial dysfunction.
Initial hematocrit predicts the use of blood transfusion in the pediatric trauma patient
2014, Journal of Pediatric SurgeryCitation Excerpt :In the absence of other clinical signs, the practical significance of a single Hct value is questionable. In addition, the confounding influence of intravenous fluid use makes interpretation of a single Hct value difficult [13,14,17], especially because prehospital fluids are often unknown. Patients presenting to our trauma center have a mean transport time of < 17 min, and it is unlikely that low initial Hct can be explained entirely by preadmission fluids, but we cannot absolutely rule out this possibility.
Admission hematocrit and transfusion requirements after trauma
2013, Journal of the American College of SurgeonsCitation Excerpt :Kass and colleagues24 found that infusion of 15 mL/kg for 30 minutes instantly decreased the Hct of healthy volunteers by 4.5% ± 1.3%. Greenfield and colleagues25 found similar results, with a mean Hct drop of 4.5% to 6.4% after 10-, 20- and 30-mL/kg saline boluses. Knottenbelt27 reported reduced Hb in trauma patients with moderate (11.8 g/dL) and severe shock (9.9 g/dL) vs those without shock (12.8 g/dL).
Resuscitation volume in paediatric non-haemorrhagic blunt trauma
2012, InjuryCitation Excerpt :The haematocrit value was the only independent factor that predicted the RV administered in this patient population as shown by regression analysis, and might be helpful for monitoring intravascular fluid volume in these patients. The effect of intravascular crystalloid administration in decreasing the haematocrit value in human volunteers has been demonstrated previously.30 Adult trauma patients had a decrease in haematocrit values of 5 from baseline with intravascular volume replacement, and the measured haematocrit was decreased further when associated with significant haemorrhage.
Presented at the American College of Emergency Physicians Scientific Assembly in San Francisco 1987.