Table 2

Certainty of evidence assessment

Participants (studies) follow-upRisk of biasInconsistencyIndirectnessImprecisionPublication biasOverall certainty of evidenceStudy event rates (%)Relative effect (95% CI)Anticipated absolute effects
With no active implementation strategiesWith active implementation strategiesRisk with no active implementation strategiesRisk difference with active implementation strategies
Proportion of patients who received VTE prophylaxis
3047 (4 observational studies)SeriousNot seriousNot seriousSeriousNone⨁⨁ Low832 of 1324 (62.8%)1442 of 1723 (83.7%)OR 2.94 (1.68 to 5.15)628 per 1000204 more per 1000 (from 111 more to 269 more)
VTE events
3047 (4 observational studies)SeriousSeriousNot seriousSeriousNone⨁ Very low51 of 1324 (3.9%)43 of 1723 (2.5%)OR 0.86 (0.43 to 1.71)39 per 10005 fewer per 1000 (from 22 fewer to 26 more)
  • VTE, venous thromboembolism.