Table 2

Contingency table of CAT+ (reference standard) versus MHPA (MH diagnosis; index test)

CAT+ (≥3 U RBC/60 min in 24 hours)CAT− (<3 U RBC/60 min in 24 hours)
MHPA9745
No MHPA41764
Sensitivity=70.3% (95% CI 62.2% to 77.3%)
Specificity=94.4% (95% CI 92.6% to 95.8%)
PPV=68.3% (95% CI 60.3% to 75.4%)
NPV=94.9% (95% CI 93.2% to 96.2%)
FPR=45/(45+764)=5.56%
FNR=41/(41+97)=29.71%
LR=12.6
  • CAT, critical admission threshold; FNR, false negative rate; FPR, false positive rate; LR, likelihood ratio; MH, major hemorrhage; NPV, negative predictive value; PPV, positive predictive value; RBC, packed red blood cells.