Table 2

Risk reduction threshold analysis assessing the PPs, BFs, and LOEs at each risk level evaluated

TimeMeasureRR <1RR <0.9RR <0.8RR <0.7RR <0.6RR <0.5
1 hourPP (%)969287786344
BF21.211.26.63.51.70.8
LOEStrongStrongSubstantialSubstantialAnecdotalAnecdotal
3 hoursPP (%)999794887451
BF142.038.215.87.12.81.0
LOEDecisiveVery strongStrongSubstantialAnecdotalAnecdotal
6 hoursPP (%)948671522610
BF14.95.92.51.10.40.1
LOEStrongSubstantialAnecdotalAnecdotalAnecdotalAnecdotal
12 hoursPP (%)92836746236
BF11.44.92.00.90.30.1
LOEStrongSubstantialAnecdotalAnecdotalAnecdotalAnecdotal
18 hoursPP (%)96907754298
BF26.49.13.31.20.40.1
LOEStrongSubstantialSubstantialAnecdotalAnecdotalAnecdotal
24 hoursPP (%)94856846225
BF15.55.62.20.90.30.5
LOEStrongSubstantialSubstantialAnecdotalAnecdotalAnecdotal
  • *LOE based on Jeffery’s Scale of Evidence.

  • †RR values in favor of 1:1:1 compared with 1:1:2 resuscitation strategy with lower RR thresholds representing a stronger benefit seen within a balanced approach.

  • BF, Bayes factor; LOE, level of evidence; PP, posterior probability; RR, risk ratio.