Table 2

Regulatory challenges addressed

Variable	Frequency	Per cent (%)
Informed consent	225	78
Research ethics	187	65
Institutional review board	158	55
Human subjects protection	156	54
Enrollment	152	53
Exception from informed consent	147	51
Legally authorized representative	144	50
Patient safety	118	41
Community consultation	117	40
Waiver of informed consent	116	40
Recruitment challenges	112	39
Patient perception	88	30
Liability	44	15
Participant incentives	38	13
Common rule	32	11