Benzodiazepine dosing and metabolism for AWS
| Drug | Routes | Onset (min) | PO dosing for AWS | IV dosing for AWS | Half-life (hours) | Metabolism |
| Diazepam | PO, intravenous, IM, rectal | IV: 2–5 | 10 mg 3–4 times per day | 5–10 mg every 10–15 min | 43 | Liver |
| Chlordiazepoxide | PO, intravenous, IM | PO: 30–120 | 50–100 mg, repeated up to 300 mg in 24 hours | NA | 10 | Liver |
| Lorazepam | PO, intravenous, IM | IV: 15–20 | 2–4 mg q 1 hour | 1–4 mg every 5–15 min | 14 | Liver |
AWS, alcohol withdrawal syndrome; IM, intramuscular; PO, oral.