Significant associations between demographic and clinical characteristics and alcohol and drug use comorbidities
| Comorbidity and variables | OR | 95% CI |
| Alcohol | – | – |
| Tobacco Use | 2.01 | 1.37 to 2.96 |
| Preinjury unemployment | 0.67 | 0.48 to 0.93 |
| Opioids | – | – |
| Preinjury unemployment | 2.09 | 1.26 to 3.47 |
| Female | 0.40 | 0.22 to 0.72 |
| Age | 0.96 | 0.94 to 0.98 |
| Non-white race | 0.24 | 0.12 to 0.48 |
| Stimulants | – | – |
| Tobacco use | 1.95 | 1.33 to 2.84 |
| Not married | 1.89 | 1.19 to 3.02 |
| Preinjury unemployment | 1.84 | 1.29 to 2.62 |
| Intentional Injury | 1.80 | 1.24 to 2.62 |
| Age | 0.98 | 0.96 to 0.99 |
| Cannabis | – | – |
| Tobacco use | 1.52 | 1.06 to 2.19 |
| Intentional injury | 1.73 | 1.24 to 2.40 |
| Age | 0.96 | 0.94 to 0.97 |
| At least some college | 0.59 | 0.40 to 0.87 |
| Injury severity score | 0.98 | 0.97 to 0.99 |
All variables presented are statistically significant with p<0.05.