Unadjusted outcomes by FICB status
| Outcome, % (n) | FICB (n=381) | No FICB (n=136) | P value |
| Delirium through 48 hours postoperative | 5.8% (22) | 4.4% (6) | 0.55 |
| Pain NRS score, mean (SE) | |||
| Preoperative pain | 3.9 (0.13) | 4.7 (0.23) | 0.002 |
| Postoperative pain | 2.9 (0.12) | 3.5 (0.24) | 0.03 |
| OME, median (IQR) | |||
| Preoperative OMEs | 30.0 (12–59) | 30.0 (12–62) | 0.84 |
| Postoperative OMEs | 45.0 (15–93) | 35.0 (15–90) | 0.98 |
| Exploratory end points | |||
| Analgesic-related complication | 16.8% (64) | 14.0% (19) | 0.44 |
| Urinary retention | 4.5% (17) | 1.5% (2) | 0.18 |
| Respiratory depression | 3.4% (13) | 3.7% (5) | 1.00 |
| Hypotension | 7.1% (27) | 4.4% (6) | 0.27 |
| Constipation | 8.9% (34) | 8.8% (12) | 0.97 |
| Block failure | 4.5% (17) | – | n/a |
| Ambulation time (hours postoperative) | 19.7 (15–25) | 18.5 (15–23) | 0.40 |
| Hospital LOS, days | 5 (4–6) | 5 (4–6) | 0.90 |
| Mortality | 0.8% (3) | 0.7% (1) | 1.00 |
| ICU admission | 7.6% (29) | 9.6% (13) | 0.48 |
| Any delirium | 7.6% (29) | 4.4% (6) | 0.20 |
| Non-opioid analgesics during hospitalization, # doses* | |||
| Acetaminophen 500 mg | 9.1 (2–18) | 7.8 (2–17) | 0.74 |
| Lidocaine patch | 4.5 (3–7) | 2.0 (2–4) | 0.21 |
| Propofol | 185 (100–338) | 145 (115–286) | 0.89 |
| Ketamine | 30 (30–30) | 20 (20–30) | 0.11 |
| Lidocaine intravenous | 60 (40–100) | 80 (60–100) | 0.32 |
bold values denote statistical significance p<0.05.
*Summarized if at least five patients received the non-opioid.
FICB, fascia Iliaca compartment blocks; ICU, intensive care unit; LOS, length of stay; NRS, numeric rating scale; OME, oral morphine equivalent.