Mortality overall and by severity controlling for age, gender, ISS, AO initiation SBP, admission lactate, duration of initial AO, crystalloid infusion, and CPR during AO
| Independent covariates | All patients with TBI mortality OR (95% CI) | Mild TBI mortality OR (95% CI) | Severe TBI mortality OR (95% CI) |
| RT vs. zone 1 | 3.14 (1.03 to 9.64)* | 2.49 (0.30 to 20.9) | 4.21 (0.91 to 19.5) |
| Severe vs. mild TBI | 3.03 (1.06 to 8.63)* | NA | NA |
| Age | 1.05 (1.02 to 1.08)† | 1.05 (1.01 to 1.11)* | 1.05 (1.01 to 1.09)* |
| ISS | 1.03 (0.99 to 1.06) | 1.01 (0.94 to 1.09) | 1.03 (0.99 to 1.08) |
| AO initiation SBP | 1.00 (0.98 to 1.01) | 0.98 (0.95 to 1.00) | 1.01 (0.98 to 1.03) |
| Admission lactate | 1.21 (1.07 to 1.37)† | 1.43 (1.11 to 1.85)† | 1.16 (0.99 to 1.35) |
| Crystalloids | 0.96 (0.91 to 1.01) | 0.78 (0.55 to 1.11) | 0.97 (0.91 to 1.02) |
| CPR during AO | 7.39 (2.26 to 24.2)† | 1.28 (0.16 to 10.4) | 23.7 (2.7 to 212)† |
| Duration of initial AO | 1.00 (0.99 to 1.02) | 0.98 (0.95 to 1.01) | 1.01 (0.99 to 1.03) |
*P<0.05
†**P<0.01.
AO, aorta occlusion; CPR, cardiopulmonary resuscitation; ISS, Injury Severity Score; NA, not applicable due to stratification by TBI severity; RT, resuscitative thoracotomy; SBP, systolic blood pressure; TBI, traumatic brain injury.