Neurologic outcomes and systemic complications when controlling for age, gender, ISS, AO initiation SBP, admission lactate, duration of initial AO, crystalloid infusion, and CPR during AO in patients who survived beyond the operating room
| Independent covariates | Patients with TBI Discharge GCS t-value (95% CI) | Patients with TBI Discharge GOSE t-value (95% CI) | Patients with TBI with systemic complications OR (95% CI) |
| RT vs. zone 1 | −0.62 (−4.68 to 3.44) | −0.14 (−1.24 to 0.94) | 0.86 (0.24 to 3.13) |
| Severe vs. mild TBI | −1.73 (−5.0 to 1.55) | −0.20 (−1.16 to 0.76) | 1.06 (0.35 to 3.23) |
| Age | −0.05 (−0.13 to 0.04) | −0.01 (−0.03 to 0.02) | 0.99 (0.96 to 1.02) |
| ISS | −0.04 (−0.14 to 0.07) | 0.01 (−0.02 to 0.04) | 1.00 (0.97 to 1.04) |
| AO initiation SBP | −0.002 (−0.05 to 0.05) | 0.001 (−0.01 to 0.01) | 0.98 (0.96 to 0.99)** |
| Admission lactate | −0.29 (−0.69 to 0.12) | −0.09 (−0.19 to 0.01) | 1.00 (0.89 to 1.12) |
| Crystalloids | 0.24 (−0.17 to 0.64) | −0.08 (−0.03 to 0.18) | 1.24 (1.06 to 1.44)** |
| CPR during AO | −3.60 (−7.79 to 0.59) | −0.52 (−1.65 to 0.60) | 0.33 (0.08 to 1.35) |
| Duration of initial AO | −0.02 (−0.06 to 0.01) | −0.004 (−0.01 to 0.004) | 0.98 (0.96 to 0.99)* |
*P<0.05, **P<0.01.
AO, aorta occlusion; CPR, cardiopulmonary resuscitation; GCS, Glasgow Coma Scale; GOSE, Glasgow Outcome Scale Extended; ISS, Injury Severity Score; RT, resuscitative thoracotomy; SBP, systolic blood pressure; TBI, traumatic brain injury.