Table 4

Outcomes of patients with polymicrobial or monomicrobial NSTI

Outcome variableMonomicrobial (n=54)Polymicrobial (n=27)P value
90-day mortality, n (%)26 (48.1)9 (33.3)0.24
In-hospital mortality, n (%)22 (40.7)7 (25.9)0.22
Length of ICU stay (days), median (IQR)4.5 (0.0–15.7)0.0 (0.0–4.5)0.81
Length of hospitalization (days), median (IQR)23.5 (12.7–42.0)32.8 (12.0–45.0)0.04
Mechanical ventilation, n (%)31 (62.0)11 (50.0)0.43
Vasopressor use, n (%)27 (65.9)7 (35.0)0.03
Amputation at 90 days, n (%)5 (9.3)5 (18.7)0.23
Further surgery at 90 days (after debridement at diagnosis),* median (IQR)2 (0–10)3 (0–6)0.056
  • *Including amputation and debridement of the involved site.

  • ICU, intensive care unit; NSTI, necrotizing soft tissue infection.