Table 3

Details regarding enoxaparin administration

Total (N=163)TBI (n=41)Non-TBI (n=122)P value
Time to initiate enoxaparin, median d2 (1–6)7.5 (3–10)1.5 (1–4)<0.01
Days to first anti-Xa level drawn, median d4 (2–7)9 (5–11.5)3 (2–6)<0.01
Within goal at first measure, n (%)63 (38.7)15 (36.6)48 (39.3)0.75
Days to reach goal (from admission), median d6 (6–13)11 (7–16)5 (2–10)<0.01
Dose adjustments to reach goal, median n1 (0–1)1 (0–2)1 (0–1)0.61
Optimal dose based on anti-Xa levels (mg), median40 (30–40)40 (30–50)40 (30–40)0.73
Patients given prophylactic unfractionated heparin prior to enoxaparin, n (%)33 (20.2)19 (46.3)14 (11.5)<0.01
Days to initiate prophylactic unfractionated heparin, median d3 (1–3)3 (2–4)1 (0–3)0.01
Patients who underwent IVC filter placement, n (%)8 (4.9)4 (9.8)4 (3.3)0.11
Duplex ultrasonography ordered based on clinical suspicion, n (%)50 (30.7)13 (31.7)37 (30.3)0.87
Days to first duplex ultrasonography performed, median d7.5 (5–12)10 (6.5–13)6 (4–11)0.07
Chest CT angiography ordered, n (%)22 (13.5)6 (14.6)16 (13.1)0.81
Days to first chest CT angiography based on clinical suspicion, median d8 (5–18)16.5 (8–22)7 (5–12)0.25
  • IVC, inferior vena cava; TBI, traumatic brain injury.