Demographics of largest 15 US metropolitan areas
| Population | Size (km2) | Population density (person/km2) | High-level trauma centers | High-level center population density (person/center) | High-level center geographic density (km2/center) | |
| New York | 8 443 713 | 485.1 | 17406.1 | 16 | 527 732 | 30.3 |
| Los Angeles | 3 990 469 | 4754.1 | 5291.7 | 14 | 285 034 | 53.9 |
| Chicago | 2 705 988 | 365.8 | 7397.5 | 10 | 270 599 | 36.6 |
| Houston | 2 295 982 | 1025.8 | 2238.2 | 4 | 573 996 | 256.5 |
| Phoenix | 1 610 071 | 832.8 | 1933.3 | 9 | 178 897 | 92.5 |
| Philadelphia | 1 575 522 | 215.8 | 7300.8 | 7 | 225 075 | 30.8 |
| San Antonio | 1 486 521 | 741.7 | 2004.2 | 2 | 743 261 | 370.9 |
| San Diego | 1 401 932 | 523.2 | 2679.5 | 4 | 350 483 | 130.8 |
| Dallas | 1 318 806 | 548.5 | 2404.4 | 7 | 188 401 | 78.4 |
| San Jose | 1 026 658 | 285.7 | 3593.5 | 3 | 342 219 | 95.2 |
| Austin | 935 755 | 503.2 | 1859.6 | 4 | 233 939 | 125.8 |
| Jacksonville | 878 907 | 1202.5 | 730.9 | 4 | 219 727 | 300.6 |
| San Francisco | 870 044 | 75.5 | 11523.8 | 1 | 870 044 | 75.5 |
| Columbus | 867 628 | 351.5 | 2468.4 | 4 | 216 907 | 87.9 |
| Indianapolis | 857 637 | 581.6 | 1474.6 | 3 | 285 879 | 193.9 |
All demographic data were estimates from 2018.