Table 1

Patient demographics, resuscitation, and outcome parameters

DemographicsTotal cohort
(n=297)
No infectious complications
(n=163)
Infectious complications
(n=134)
P value
Age (years)46 (27–60)44 (24–59)50 (30–61)0.08
Gender (% male)216 (73)111 (68)105 (78)0.05
MOI (%blunt)286 (96)154 (94)132 (99)0.12
ISS29 (22–35)29 (22–34)29 (22–36)0.48
AIS head3 (1–4)3 (1–4)3 (1–4)0.72
AIS face0 (0–2)0 (0–2)0 (0–1)0.15
AIS chest3 (2–4)3 (2–4)3 (2–4)0.12
AIS abdomen2 (0–3)2 (0–2)2 (0–3)0.75
AIS extr /pelvis2 (1–3)2 (1–3)2 (0–3)0.11
AIS external0 (0–1)0 (0–1)0 (0–1)0.30
Pelvic fracture93 (31)42 (25)51 (38)0.02*
Urgent laparotomy71 (24)29 (18)42 (31)0.009*
 ED parameters
 SBP (mm Hg)120 (100–136)121 (100–142)117 (96–132)0.08
 DBP (mm Hg)75 (60–86)78 (60–90)74 (60–83)0.05
 Temperature (0C)35.5 (34.4–36.5)35.4 (34.3–36.5)35.5 (34.4–36.5)0.78
 Hb (mmol/L)8.0 (7.2–8.9)8.0 (7.4–9.1)8.0 (7.2–8.9)0.48
 Leukocytes (x109/L)15.3 (11.1–20.1)15.3 (11.6–19.9)15.3 (9.8–20.6)0.56
 Platelets(x109/L)235 (190–281)233 (190–288)235 (187–277)0.67
 PT15.2 (13.9–17.3)15.1 (14.0–17.0)15.5 (13.9–17.9)0.34
 pH7.31 (7.26–7.37)7.32 (7.26–7.38)7.30 (7.25–7.35)0.15
 PaCO2 (mm Hg)46 (41–54)46 (40–52)47 (42–54)0.19
 PaO2 (mm Hg)202 (105–302)221 (100–329)198 (106–277)0.35
 BD (mmol/L)3.0 (0.0–6.0)2.5 (0.0–6.0)3.0 (0.0–6.0)0.63
 Sat (%)100 (97–100)100 (97–100)100 (98–100)0.98
 ICU Parameters
 SBP (mm Hg)119 (105–136)120 (106–136)119 (105–137)0.82
 DBP (mm Hg)65 (56–74)66 (56–75)65 (55–73)0.38
 Temperature (0C)35.3 (34.5–36.0)35.4 (34.3–36.1)35.3 (34.5–35.9)0.70
 Hb (mmol/L)7.6 (6.8–8.3)7.6 (6.8–8.3)7.5 (6.8–8.2)0.71
 pH7.33 (7.29–7.38)7.34 (7.30–7.38)7.33 (7.28–7.38)0.68
 PaCO2 (mm Hg)43 (38–47)43 (39–47)43 (38–47)0.73
 PaO2 (mm Hg)150 (114–192)153 (116–190)144 (108–198)0.36
 BD (mmol/L)3.5 (1.5–5.7)3.2 (1.4–5.5)4.0 (1.5–6.1)0.23
 Sat (%)98 (98–99)98 (98–99)98 (97–99)0.10
 UO (ml)150 (80–300)150 (80–310)145 (71–295)0.54
Resuscitation
 Crystalloids (L)
 <8 hours4.7 (2.4–6.3)4.5 (2.3–6.3)4.8 (2.7–6.3)0.31
 <24 hours7.4 (5.1–10.4)7.3 (4.6–10.3)7.9 (5.5–10.4)0.19
 PRBC (u)
 <8 hours1 (0–4)0 (0–3)2 (0–6)0.03*
 <24 hours1 (0–5)1 (0–4)2 (0–7)0.06
 FFP (u)
 <8 hours0 (0–4)0 (0–3)1 (0–5)0.04*
 <24 hours0 (0–5)0 (0–4)2 (0–7)0.06
 PLT (u)†
 <8 hours0 (0–1)0 (0–0)0 (0–1)0.04*
 <24 hours0 (0–1)0 (0–1)0 (0–1)0.03*
 Outcome
 Ventilator days7 (3–11)5 (2–8)10 (5–15)<0.001*
 ICU-LOS (days)8 (4–14)6 (3–10)11 (6–17)<0.001*
 H-LOS (days)21 (13–33)16 (10–24)30 (20–44)<0.001*
 MODS56 (19)21 (13)35 (25)0.005*
 ARDS15 (5)5 (3)10 (7)0.11
 Mortality44 (15)27 (17)17 (12)0.41
  • Data are expressed as median (IQR) or absolute numbers (%).

  • *Statistically significant.

  • †1 unit of platelets contains five donors.

  • AIS, Abbreviated Injury Scale; ARDS, acute respiratory dysfunction syndrome; BD, base deficit; DBP, diastolic blood pressure; FFP, fresh frozen plasma; Hb, hemoglobin; H-LOS, hospital length of stay; ICU, intensive care unit; ISS, Injury Severity Score; LOS, length of stay; MODS, multiple organ dysfunction syndrome; MOI, mechanism of injury; PaCO2, partial pressures of carbon dioxide; PaO2, partial pressures of oxygen; PLT, platelets; PRBC, packed red blood cells; PT, prothrombin time; Sat, saturation; SBP, systolic blood pressure; UO, urinary output first hour in ICU.