Demographic data and group characteristics for all trauma patients with a MT and ISS >10 who received TXA, did not receive TXA and those who were missing TXA information from 2009 to 2014
| Characteristic | TXA1 (318) | TXA0 (38) | TXA-Missing (264) |
| Demographic data | |||
| Age mean (SD) | 24.5 (4.6) | 25.6 (5.2) | 25.0 (5.1) |
| Gender (% male) | 100% | 100% | 99.2% |
| Service b ranch | |||
| Air force, no. (%) | 3 (0.9%) | 1 (2.6%) | 9 (3.4%) |
| Army, no. (%) | 155 (48.7%) | 27 (71.1%) | 159 (60.2%) |
| Marine, no. (%) | 152 (47.8%) | 10 (26.3%) | 91 (34.5%) |
| Navy, no. (%) | 8 (2.5%) | 0 (0%) | 5 (1.9%) |
| Injury t ype | |||
| Blunt, no. (%) | 16 (5.0%) | 3 (7.9%) | 34 (12.9%) |
| Burn, no. (%) | 5 (1.6%) | 2 (5.3%) | 1 (0.4%) |
| Penetrating, no. (%) | 297 (93.4%) | 33 (86.8%) | 229 (86.7%) |
| Mechanism of injury | |||
| Bullet/GSW/Firearm, no. (%) | 33 (10.4%) | 6 (15.8%) | 29 (11.0 %) |
| Crush, no. (%) | 1 (0.3%) | 0 (0%) | 1 (0.4%) |
| Explosive, no. (%) | 279 (87.7%) | 31 (81.6%) | 229 (86.7%) |
| Helicopter crash, no. (%) | 3 (0.9%) | 0 (0%) | 0 (0%) |
| Knife or sharp object, no. (%) | 1 (0.3%) | 0 (0%) | 0 (0%) |
| Machinery/Equipment, no. (%) | 0 (0%) | 0 (0%) | 1 (0.4%) |
| MVC, no. (%) | 1 (0.3%) | 0 (0%) | 3 (1.1%) |
| Pedestrian, no. (%) | 0 (0%) | 1 (2.6%) | 0 (0%) |
| Plane crash, no. (%) | 0 (0%) | 0 (0%) | 1 (0.4%) |
| Composite ISS | |||
| Mean (SD) | 30.7 (13.0) | 31.9 (16.0) | 29.6 (12.6) |
| AIS | |||
| Head/Neck mean (SD) | 1.3 (1.5) | 1.3 (1.6) | 1.5 (1.5) |
| Face mean (SD) | 0.8 (0.7) | 0.7 (0.9) | 0.7 (0.8) |
| Chest/Thorax mean (SD) | 1.2 (1.6) | 1.8 (1.7) | 1.5 (1.6) |
| Abdomen mean (SD) | 1.9 (1.5) | 1.9 (1.5) | 1.8 (1.5) |
| Extremities mean (SD) | 3.7 (1.3) | 3.2 (1.5) | 3.4 (1.3) |
| Skin mean (SD) | 1.5 (0.7) | 1.6 (1.2) | 1.5 (0.9) |
| Estimated blood loss (m L ) in first 24 hours | |||
| Mean (SD) | 1996.8 (2489.0) | 2881.3 (2940.2) | 2071.8 (2321.8) |
| F irst 24 hours transfusion, units | |||
| PRBC mean (SD) | 24.2 (15.2) | 24.4 (15.9) | 22.2 (12.7) |
| Whole blood mean (SD) | 1.2 (3.5) | 3.3 (7.2) | 1.8 (5.5) |
| FFP mean (SD) | 22.3 (14.7) | 20.6 (18.0) | 19.2 (12.1) |
| Platelets mean (SD) | 4.7 (3.7) | 4.0 (4.2) | 3.8 (2.9) |
| Cryoprecipitate mean (SD) | 9.5 (12.6) | 10.6 (15.4) | 7.2 (8.5) |
| Miscellaneous | |||
| Tourniquet used, no. (%) | 244 (76.7%) | 29 (76.3%) | 175 (66.3%) |
| Days in ICU, mean (SD) | 13.8 (13.4) | 24.8 (68.3) | 12.1 (11.3) |
| Days in hospital, mean (SD) | 34.7 (35.1) | 53.5 (84.8) | 37.0 (38.4) |
| Days on ventilator, mean (SD) | 8.2 (8.2) | 11.9 (19.1) | 7.3 (8.2) |
AIS, Abbreviated Injury Score; FFP, fresh frozen plasma; GSW, gun shot wound; ICU, intensive care unit; ISS, injury severity score; MT, massive transfusion; MVC, motor vehicle crash; PRBC, packed red blood cells; SD, standard deviation; TXA0, tranexamic acid not administered during treatment; TXA1, tranexamic acid administered during treatment; TXA-Missing, tranexamic acid administration information is missing from medical chart.