Multivariable analysis of predictors for acute respiratory distress syndrome in patients with trauma-induced lung contusion*
OR | 95% CI | P value | |
Demographics | |||
Age | |||
16–25 | Baseline | ||
26–45 | 1.05 | 0.97 to 1.13 | 0.2 |
46–65 | 1.15 | 1.05 to 1.25 | 0.002 |
66–75 | 1.36 | 1.18 to 1.57 | <0.001 |
>75 | 1.58 | 1.35 to 1.84 | <0.001 |
Male | 1.31 | 1.23 to 1.40 | <0.001 |
Race | |||
White | Baseline | ||
Black | 0.96 | 0.88 to 1.05 | 0.4 |
Hispanic or Latino | 0.97 | 0.86 to 1.09 | 0.6 |
Other | 1.00 | 0.85 to 1.19 | 0.96 |
Insurance | |||
Medicaid | Baseline | ||
Medicare | 0.85 | 0.76 to 0.96 | 0.008 |
Private | 0.94 | 0.86 to 1.02 | 0.2 |
Self-pay | 0.72 | 0.64 to 0.81 | <0.001 |
Extrathoracic risk factors | |||
EtOH | |||
No-confirmed | Baseline | ||
Not tested | 0.90 | 0.82 to 0.99 | 0.03 |
Below 0.08 | 0.84 | 0.74 to 0.96 | 0.01 |
Above 0.08 | 0.93 | 0.85 to 1.01 | 0.09 |
Drugs | |||
No-confirmed | Baseline | ||
Not tested | 0.83 | 0.75 to 0.92 | 0.001 |
Yes-prescription | 1.06 | 0.94 to 1.21 | 0.3 |
Yes-illegal | 1.15 | 1.05 to 1.26 | 0.003 |
Injury Severity Score | 1.04 | 1.04 to 1.04 | <0.001 |
Lowest ED systolic blood pressure | 1.00 | 1.00 to 1.00 | 0.5 |
Temperature | 1.01 | 1.00 to 1.02 | 0.2 |
GCS motor score | 0.79 | 0.78 to 0.81 | <0.001 |
Thoracic risk factors | |||
Traumatic rib fracture | |||
No rib fractures | Baseline | ||
1 rib fracture | 1.09 | 0.98 to 1.21 | 0.1 |
2 rib fractures | 1.08 | 0.96 to 1.21 | 0.2 |
3 rib fractures | 0.85 | 0.74 to 0.99 | 0.04 |
4 rib fractures | 1.16 | 1.03 to 1.30 | 0.1 |
5 rib fractures | 1.15 | 0.99 to 1.34 | 0.06 |
6 rib fractures | 1.35 | 1.16 to 1.56 | <0.001 |
7 rib fractures | 1.50 | 1.28 to 1.76 | <0.001 |
≥8 rib fractures | 1.51 | 1.37 to 1.67 | <0.001 |
Rib fracture (NOS) | 1.39 | 1.26 to 1.55 | <0.001 |
Flail chest | 2.09 | 1.87 to 2.33 | <0.001 |
Comorbidities | |||
Alcoholism | 1.53 | 1.38 to 1.68 | <0.001 |
Bleeding disorder | 1.79 | 1.56 to 2.05 | <0.001 |
Congestive heart failure | 1.42 | 1.17 to 1.73 | <0.001 |
Current smoker | 0.97 | 0.89 to 1.05 | 0.4 |
Diabetes mellitus | 1.30 | 1.17 to 1.44 | <0.001 |
History of angina within 30 days | 1.82 | 1.16 to 2.83 | 0.009 |
History of myocardial infarction | 1.01 | 0.77 to 1.31 | 0.96 |
Hypertension requiring medications | 1.24 | 1.15 to 1.35 | <0.001 |
Obesity | 1.77 | 1.60 to 1.95 | <0.001 |
History of respiratory disease | 1.53 | 1.37 to 1.70 | <0.001 |
*C-statistic=0.85.
ED, emergency department; EtOH, preinjury alcohol consumption; GCS, Glasgow Coma Scale; NOS, not otherwise specified.