Multivariable analysis of predictors for acute respiratory distress syndrome in trauma patients*
OR | 95% CI | P value | |
Demographics | |||
Age | |||
16–25 | Baseline | ||
26–45 | 1.06 | 1.02 to 1.10 | 0.002 |
46–65 | 1.19 | 1.15 to 1.24 | <0.001 |
66–75 | 1.43 | 1.34 to 1.52 | <0.001 |
>75 | 1.48 | 1.39 to 1.58 | <0.001 |
Male | 1.35 | 1.31 to 1.39 | <0.001 |
Race | |||
White | Baseline | ||
Black | 0.96 | 0.93 to 1.00 | 0.046 |
Hispanic or Latino | 0.91 | 0.86 to 0.97 | 0.003 |
Other | 1.05 | 0.97 to 1.13 | 0.2 |
Insurance | |||
Medicaid | Baseline | ||
Medicare | 0.89 | 0.84 to 0.94 | <0.001 |
Private | 0.93 | 0.89 to 0.96 | <0.001 |
Self-pay | 0.71 | 0.67 to 0.75 | <0.001 |
Extrathoracic risk factors | |||
EtOH | |||
No-confirmed | Baseline | ||
Not tested | 0.75 | 0.71 to 0.78 | <0.001 |
Below 0.08 | 0.90 | 0.85 to 0.96 | 0.001 |
Above 0.08 | 0.86 | 0.82 to 0.89 | <0.001 |
Drugs | |||
No-confirmed | Baseline | ||
Not tested | 0.77 | 0.72 to 0.83 | <0.001 |
Yes-prescription | 1.05 | 0.98 to 1.11 | 0.1 |
Yes-illegal | 1.27 | 1.20 to 1.35 | <0.001 |
Injury Severity Score | 1.05 | 1.05 to 1.05 | <0.001 |
Lowest ED systolic blood pressure | 1.00 | 1.00 to 1.00 | 0.7 |
Temperature | 1.00 | 1.00 to 1.01 | 0.3 |
GCS motor component score | 0.73 | 0.72 to 0.73 | <0.001 |
Thoracic risk factors | |||
Trauma-induced lung contusion | 1.46 | 1.40 to 1.51 | <0.001 |
Traumatic rib fracture | |||
No rib fractures | Baseline | ||
1 rib fracture | 1.45 | 1.37 to 1.54 | <0.001 |
2 rib fractures | 1.46 | 1.37 to 1.56 | <0.001 |
3 rib fractures | 1.31 | 1.21 to 1.41 | <0.001 |
4 rib fractures | 1.50 | 1.40 to 1.60 | <0.001 |
5 rib fractures | 1.55 | 1.42 to 1.69 | <0.001 |
6 rib fractures | 1.71 | 1.55 to 1.87 | <0.001 |
7 rib fractures | 1.83 | 1.65 to 2.02 | <0.001 |
≥8 rib fractures | 1.84 | 1.73 to 1.95 | <0.001 |
Rib fracture (NOS) | 1.80 | 1.70 to 1.90 | <0.001 |
Flail chest | 2.60 | 2.42 to 2.80 | <0.001 |
Comorbidities | |||
Alcoholism | 1.72 | 1.65 to 1.80 | <0.001 |
Bleeding disorder | 1.62 | 1.53 to 1.70 | <0.001 |
Congestive heart failure | 1.87 | 1.76 to 1.99 | <0.001 |
Current smoker | 0.92 | 0.88 to 0.96 | <0.001 |
Diabetes mellitus | 1.19 | 1.14 to 1.24 | <0.001 |
History of angina within 30 days | 2.21 | 1.93 to 2.53 | <0.001 |
History of myocardial infarction | 1.14 | 1.04 to 1.25 | 0.005 |
Hypertension requiring medications | 1.25 | 1.21 to 1.30 | <0.001 |
Obesity | 1.64 | 1.56 to 1.72 | <0.001 |
History of respiratory disease | 1.69 | 1.62 to 1.76 | <0.001 |
*C-statistic=0.85.
ED, emergency department; EtOH, preinjury alcohol consumption; GCS, Glasgow Coma Scale; NOS, not otherwise specified.