Patients requiring 0u pRBC (n=237) | Patients requiring 1u–4u pRBC (n=143) | Patients requiring ≥5u pRBC (n=82) | |
Preoperative | |||
HR (bpm) | 91±18 | 101±21* | 112±29*† |
SBP (mm Hg) | 134±21 | 123±25* | 114±30*† |
pH (u) | 7.32±0.07 | 7.27±0.08* | 7.13±0.16*† |
BE (mmol/L) | −3.2±3.7 | −5.5±3.9* | −10.9±6.1*† |
Lactate (mmol/L) | 3.4±2.2 | 4.1±5.3 | 8.3±4.7*† |
Hct (%) | 38.1±5.6 | 33.1±6.2* | 32.3±7.0* |
GFR (mL/min/1.73 m2) | 81±21 | 72±24* | 68±37* |
Perioperative | |||
Required vasopressors, n (%) | 120 (51) | 92 (64)* | 58 (70)* |
Required >1 vasopressor, n (%) | 17 (7) | 27 (19)* | 28 (34)*† |
Left OR on vasopressors, n (%) | 1 (0) | 2 (1) | 8 (10)*† |
Postoperative | |||
HR (bpm) | 94±19 | 96±19 | 102±27* |
SBP (mm Hg) | 136±26 | 132±26 | 124±26* |
pH (u) | 7.29±0.06 | 7.31±0.05 | 7.33±0.09* |
BE (mmol/L) | −3.6±2.8 | −3.4±2.8 | −1.3±4.8*† |
Lactate (mmol/L) | 2.5±1.3 | 2.8±1.7 | 5.1±4.7*† |
Hct (%) | 36.3±5.8 | 34.3±5.9* | 31.1±7.9*† |
GFR (mL/min/1.73 m2) | 95±26 | 87±31* | 73±31*† |
Na+ (mmol/L) | 138±3 | 139±4 | 142±4*† |
Cl− (mmol/L) | 107±3 | 108±4 | 106±4 |
All data expressed as mean±SD.
*P<0.05 vs. 0 pRBC.
†P<0.05 vs. 1–4 pRBC.
BE, base excess, bpm, beats per minute; Cl-, chloride; GFR, glomerular filtration rate, HR, heart rate, Hct, hematocrit, Na+, sodium, OR, operating room, SBP, systolic blood pressure, pRBC, packed red blood cells; u, unit.