MAP (mm Hg) | |||||
---|---|---|---|---|---|
Time point | |||||
Group | Baseline | Shock30 | T30 | T60 | T120 |
Sham | 70.5±2.4 | 77.0±3.7 | 75.5±3.1 | 72.5±2.3 | 71±1.0 |
Shock-only | 72.9±2.8 | 40.0±1.1a | 40.0±2.4a | 49.0±4.0b | 43.3±8.6c |
Shock+LRS | 73.6±1.2 | 42.8±1.3a | 60.0±2.5b,d | 58.0±2.6c | 53.0±2.2 |
Shock+Terli | 70.8±1.4 | 41.5±1.0a | 64.2±2.2b,d | 60.1±3.4c | 56.9±3.7 |
Values are mean±SE.
ap<0.001 vs sham; bp<0.01 vs sham; cp<0.05 vs sham; dp<0.05 vs shock30.
MAP, mean arterial pressure; Sham, anesthetized but not subjected to hemorrhagic shock; Shock+LRS, subjected to hemorrhagic shock and subsequently treated with LRS at a volume equal to three times that of the blood removed; Shock+Terli, subjected to hemorrhagic shock and subsequently treated with a 2 mg bolus of terlipressin; Shock30, 30 min after achieving the target MAP (immediately prior to treatment); Shock-only, subjected to hemorrhagic shock and left untreated; T120, 120 min after treatment; T30, 30 min after treatment; T60, 60 min after treatment.