RT Journal Article SR Electronic T1 Step-up approach for the management of pancreatic necrosis: a review of the literature JF Trauma Surgery & Acute Care Open JO Trauma Surg Acute Care Open FD BMJ Publishing Group Ltd SP e000308 DO 10.1136/tsaco-2019-000308 VO 4 IS 1 A1 Melanie Kay Sion A1 Kimberly A Davis YR 2019 UL http://tsaco.bmj.com/content/4/1/e000308.abstract AB Infected necrotizing pancreatitis is a challenging condition to treat because of the profound inflammatory response these patients undergo which can then be exacerbated by interventions. Treatment of this condition has evolved in timing of intervention as well as method of intervention and includes less invasive options for treatment such as percutaneous drainage and endoscopic drainage, in addition to less invasive endoscopic and video-assisted or laparoscopic debridements. The precise optimal treatment strategy for these patients is an ongoing topic of discussion and may be different for each patient as this is a heterogenous condition.