User profiles for Y. Uchiyama

Yusuke Uchiyama

Kobe University
Verified email at harbor.kobe-u.ac.jp
Cited by 4731

Extremely fast acceleration of cosmic rays in a supernova remnant

Y Uchiyama, FA Aharonian, T Tanaka, T Takahashi… - Nature, 2007 - nature.com
Galactic cosmic rays (CRs) are widely believed to be accelerated by shock waves associated
with the expansion of supernova ejecta into the interstellar medium 1 . A key issue in this …

[HTML][HTML] Autophagy–physiology and pathophysiology

Y Uchiyama, M Shibata, M Koike, K Yoshimura… - Histochemistry and cell …, 2008 - Springer
… Seglen 1982; Seglen and Gordon 1982), cell death that is accompanied by autophagy and
inhibited by 3-MA is suggested to be autophagic cell death (Bursch et al. 1996; Uchiyama

Autophagic cell death and its execution by lysosomal cathepsins

Y Uchiyama - Archives of histology and cytology, 2001 - jstage.jst.go.jp
… KOMINAMI and Y. UCHIYAMA: Delayed neuronal death in the CA1 pyramidal cell layer
of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci. …

[HTML][HTML] Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons

M Komatsu, T Ueno, S Waguri, Y Uchiyama… - Cell Death & …, 2007 - nature.com
Investigations pursued during the last decade on neurodegenerative diseases have revealed
a common mechanism underlying the development of such diseases: conformational …

[HTML][HTML] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

…, A Kobayashi, M Yamamoto, Z Yue, Y Uchiyama… - Cell, 2007 - cell.com
Inactivation of constitutive autophagy results in formation of cytoplasmic protein inclusions
and leads to liver injury and neurodegeneration, but the details of abnormalities related to …

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

…, J Ezaki, N Mizushima, Y Ohsumi, Y Uchiyama… - The Journal of cell …, 2005 - rupress.org
Autophagy is a membrane-trafficking mechanism that delivers cytoplasmic constituents into
the lysosome/vacuole for bulk protein degradation. This mechanism is involved in the …

Loss of autophagy in the central nervous system causes neurodegeneration in mice

…, J Iwata, I Tanida, T Ueno, M Koike, Y Uchiyama… - Nature, 2006 - nature.com
Protein quality-control, especially the removal of proteins with aberrant structures, has an
important role in maintaining the homeostasis of non-dividing neural cells 1 . In addition to the …

Transplantation of in vitro‐expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

…, M Koike, Y Uchiyama, Y Toyama… - Journal of …, 2002 - Wiley Online Library
Neural progenitor cells, including neural stem cells, are a potential expandable source of
graft material for transplantation aimed at repairing the damaged CNS. Here we present the …

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

…, T Kawakami, K Arioka, H Sato, Y Uchiyama… - Nature …, 1997 - nature.com
1α,25-Dihydroxy vitamin D 3 [1α,25(OH) 2 D 3 ] an active form of vitamin D, has roles in many
biological phenomena such as calcium homeostasis and bone formation 1–3 , which are …

[PDF][PDF] Search for the lepton flavour violating decay with the full dataset of the MEG experiment: MEG Collaboration

…, GF Tassielli, F Tenchini, Y Uchiyama… - The European Physical …, 2016 - Springer
The final results of the search for the lepton flavour violating decay $$\mathrm {\mu }^+ \rightarrow
\mathrm {e}^+ \mathrm {\gamma }$$ μ + → e + γ based on the full dataset collected by …