HIF-1: a key mediator in hypoxia

J Adams, L Difazio, R Rolandelli, J Lujan… - Acta Physiologica …, 2009 - akjournals.com
The transcription factor HIF-1 is one of the principal mediators of homeostasis in human tissues
exposed to hypoxia. It is implicated in virtually every process of rapid gene expression in …

The impact of the COVID-19 pandemic on hospital admissions for trauma and acute care surgery

LT DiFazio, T Curran, JW Bilaniuk… - The American …, 2020 - journals.sagepub.com
On March 9, 2020, the Governor of New Jersey declared a state of emergency and a public
health emergency to contain the spread of the Coronavirus Disease 2019 (COVID-19) …

Hypoxia-inducible-factor-1 in trauma and critical care

DA Bogdanovski, LT DiFazio, AK Bogdanovski… - Journal of Critical …, 2017 - Elsevier
DiFazio MD, FACS a , Anastasia K. Bogdanovski BA b , Balázs Csóka PhD c , Garrett B. …
Louis DiFazio was involved in the design and acquisition of information for the purposes of …

BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking

…, AQ Kashay, A Wu, M Delaney, J Cheung, LE DiFazio… - Elife, 2022 - elifesciences.org
Quantitative descriptions of animal behavior are essential to study the neural substrates of
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed by …

[HTML][HTML] Synapsis of DNA ends by DNA-dependent protein kinase

LG DeFazio, RM Stansel, JD Griffith, G Chu - The EMBO journal, 2002 - embopress.org
… (L and M) DNA circularized by protein. (N) DNA with protein bound to one end. (O)
Unbound DNA. … Hammarsten, L.DeFazio and G.Chu, unpublished observations). …

Local concentration of fast-food outlets is associated with poor nutrition and obesity

…, E Greenberg, JB Murphy, LA DiFazio… - American journal of …, 2014 - journals.sagepub.com
Purpose. We investigated the relationship of the local availability of fast-food restaurant
locations with diet and obesity. Design. We geocoded addresses of survey respondents and fast-…

[PDF][PDF] Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4

NL Maas, KM Miller, LG DeFazio, DP Toczyski - Molecular cell, 2006 - cell.com
Histone modifications, including H3 K56 acetylation, have been implicated in DNA damage
tolerance. Here, we present evidence that Hst3 and Hst4, two paralogues of the histone …

[PDF][PDF] Dopamine errors drive excitatory and inhibitory components of backward conditioning in an outcome-specific manner

BM Seitz, IB Hoang, LE DiFazio, AP Blaisdell… - Current Biology, 2022 - cell.com
For over two decades, phasic activity in midbrain dopamine neurons was considered
synonymous with the prediction error in temporal-difference reinforcement learning. Central to this …

Spinal clearance in the difficult trauma patient: a role for screening MRI of the spine

JM Adams, MIE Cockburn, LT Difazio… - The American …, 2006 - journals.sagepub.com
Identifying spinal injuries in trauma patients with altered mental status can be difficult. CT
scanning and clinical examination are the basis of our spinal clearance, but screening “trauma …

Equestrian trauma: injury patterns vary among age groups

JW Bilaniuk, JM Adams, LT DiFazio… - The American …, 2014 - journals.sagepub.com
Patients with equestrian injuries were identified in the trauma registry from 2004 to 2007. We
a priori divided patients into three groups: 0 to 18 years, 19 to 49 years, and 50 years old or …