[HTML][HTML] Effects of Brazilian green propolis on proteinuria and renal function in patients with chronic kidney disease: a randomized, double-blind, placebo-controlled …

MAD Silveira, F Teles, AA Berretta, TR Sanches… - BMC nephrology, 2019 - Springer
Background Chronic kidney disease (CKD) is a public health problem worldwide, and
proteinuria is a well-established marker of disease progression in CKD patients. Propolis, a …

[HTML][HTML] Vitamin D deficiency aggravates chronic kidney disease progression after ischemic acute kidney injury

…, D Canale, MHM Shimizu, TR Sanches… - PloS one, 2014 - journals.plos.org
Background Despite a significant improvement in the management of chronic kidney disease
(CKD), its incidence and prevalence has been increasing over the years. Progressive renal …

[HTML][HTML] Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney …

…, JMC Capcha, AC de Bragança, TR Sanches… - Stem cell research & …, 2017 - Springer
Background Mesenchymal stromal cells (MSCs) represent an option for the treatment of acute
kidney injury (AKI). It is known that young stem cells are better than are aged stem cells at …

Erythropoietin prevents sepsis-related acute kidney injury in rats by inhibiting NF-κB and upregulating endothelial nitric oxide synthase

…, MH Shimizu, TR Sanches… - American Journal …, 2012 - journals.physiology.org
The pathophysiology of sepsis involves complex cytokine and inflammatory mediator networks,
a mechanism to which NF-κB activation is central. Downregulation of endothelial nitric …

[HTML][HTML] Effects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunction

CE Rodrigues, TR Sanches, RA Volpini, MHM Shimizu… - PloS one, 2012 - journals.plos.org
Background Despite advances in supportive care, sepsis-related mortality remains high,
especially in patients with acute kidney injury (AKI). Erythropoietin can protect organs against …

Apolipoprotein AI mimetic peptide 4F attenuates kidney injury, heart injury, and endothelial dysfunction in sepsis

RS Moreira, M Irigoyen, TR Sanches… - American Journal …, 2014 - journals.physiology.org
… response (BR) and tachycardic response (TR) at low doses of phenylephrine and sodium
nitroprusside (C), and BR and TR at high doses of phenylephrine and sodium nitroprusside (D)…

Urinary Tamm‐Horsfall protein, albumin, vitamin D‐binding protein, and retinol‐binding protein as early biomarkers of chronic kidney disease in dogs

F Chacar, M Kogika, TR Sanches… - Physiological …, 2017 - Wiley Online Library
Proteinuria is a marker and mediator of chronic kidney disease ( CKD ). In clinical practice,
the urinary protein‐to‐creatinine ratio ( UP /C) is of limited usefulness, because it indicates …

Sildenafil reduces polyuria in rats with lithium-induced NDI

TR Sanches, RA Volpini… - American Journal …, 2012 - journals.physiology.org
Lithium (Li)-treated patients often develop urinary concentrating defect and polyuria, a
condition known as nephrogenic diabetes insipidus (NDI). In a rat model of Li-induced NDI, we …

[HTML][HTML] Vitamin D deficiency aggravates nephrotoxicity, hypertension and dyslipidemia caused by tenofovir: role of oxidative stress and renin-angiotensin system

…, JG Gonçalves, MHM Shimizu, TR Sanches… - PloS one, 2014 - journals.plos.org
Vitamin D deficiency (VDD) is prevalent among HIV-infected individuals. Vitamin D has been
associated with renal and cardiovascular diseases because of its effects on oxidative stress…

Vitamin D deficiency aggravates ischemic acute kidney injury in rats

…, JG Gonçalves, MHM Shimizu, TR Sanches… - Physiological …, 2015 - Wiley Online Library
… Drs Volpini and Sanches are recipients of grants from the Fundação de Amparo à Pesquisa
do Estado de São Paulo (FAPESP, São Paulo Research Foundation, Grant nos. 2010/52294…