Deep venous thrombosis and venous thromboembolism prophylaxis

KL Buesing, B Mullapudi, KA Flowers - Surgical Clinics, 2015 - surgical.theclinics.com
Venous thromboembolism (VTE), which includes deep venous thrombosis (DVT) and pulmonary
embolism (PE), remains an all too familiar risk for surgical patients, occurring in up to 25…

Endothelial microparticles induce inflammation in acute lung injury

KL Buesing, JC Densmore, S Kaul… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Previously, we have shown that endothelial microparticles (EMPs) injected
into mice induce acute lung injury (ALI) [1]. In this study, we hypothesize that EMPs induce …

Partial splenectomy for hereditary spherocytosis: a multi-institutional review

KL Buesing, ET Tracy, C Kiernan, AC Pastor… - Journal of pediatric …, 2011 - Elsevier
BACKGROUND/PURPOSE: Partial splenectomy has emerged as a surgical option for selected
children with hereditary spherocytosis, with the goal of reducing anemia while preserving …

[HTML][HTML] A novel large animal model of smoke inhalation-induced acute respiratory distress syndrome

…, A McCain, RR Matas, EM Duarte, KL Buesing - Respiratory …, 2021 - Springer
Background Acute respiratory distress syndrome (ARDS) is multifactorial and can result
from sepsis, trauma, or pneumonia, amongst other primary pathologies. It is one of the major …

Rat model of smoke inhalation-induced acute lung injury

…, HR Weber, T Ogun, KL Buesing - BMJ Open …, 2021 - bmjopenrespres.bmj.com
Background Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a lethal
disease with limited therapeutic options and an unacceptably high mortality rate. …

Colonic Oxygen Microbubbles Augment Systemic Oxygenation and CO2 Removal in a Porcine Smoke Inhalation Model of Severe Hypoxia

…, EM Duarte, J Chen, MA Borden, KL Buesing - bioRxiv, 2021 - biorxiv.org
Inhalation injury can lead to pulmonary complications resulting in the development of respiratory
distress and severe hypoxia. Respiratory distress is one of the major causes of death in …

Testing oxygenated microbubbles via intraperitoneal and intrathoracic routes on a large pig model of LPS‐induced acute respiratory distress syndrome

…, SP Harris, KL Buesing… - Physiological …, 2022 - Wiley Online Library
With a mortality rate of 46% before the onset of COVID‐19, acute respiratory distress syndrome
(ARDS) affected 200,000 people in the US, causing 75,000 deaths. Mortality rates in …

Isolated prehospital hypotension correlates with injury severity and outcomes in patients with trauma

CD Damme, J Luo, KL Buesing - Trauma Surgery & Acute Care …, 2016 - tsaco.bmj.com
Objective Patients normotensive in the trauma bay despite documented prehospital
hypotension may not be recognized as significantly injured. The purpose of this study was to …

[HTML][HTML] Development of a multi-patient ventilator circuit with validation in an ARDS porcine model

…, AR McCain, NT Zollinger, KL Buesing… - Journal of …, 2021 - Springer
Purpose The COVID-19 pandemic threatens our current ICU capabilities nationwide. As the
number of COVID-19 positive patients across the nation continues to increase, the need for …

[HTML][HTML] Intraperitoneal oxygen microbubble therapy: A novel approach to enhance systemic oxygenation in a smoke inhalation model of acute hypoxic respiratory …

…, HR Weber, KW Foster, KL Buesing - Surgery Open …, 2023 - Elsevier
Background Patients suffering from severe acute respiratory distress syndrome (ARDS) face
limited therapeutic options and alarmingly high mortality rates. Refractory hypoxemia, a …