Parameter estimates using the Lasso method and the corresponding effect on the OR when using TXA1
| Predictor variable | VTE | Pulmonary embolism | Deep vein thrombosis | |||
| Parameter estimate | OR | Parameter estimate | OR | Parameter estimate | OR | |
| Mechanism of injury: MVC | 1.541 | 4.669 | 2.000 | 7.389 | 0.000 | – |
| Mechanism of injury: knife/sharp object | 1.405 | 4.076 | 0.000 | – | 2.762 | 15.831 |
| Injury type: burn | −0.957 | 0.384 | −0.581 | 0.559 | 0.000 | – |
| Mechanism of injury: bullet/GSW/firearm | −0.505 | 0.604 | 0.000 | – | −0.591 | 0.554 |
| Tourniquet | −0.284 | 0.753 | 0.000 | – | −0.307 | 0.736 |
| Mechanism of injury: crush | −0.197 | 0.821 | 0.000 | – | 0.000 | – |
| Service branch: air force | 0.187 | 1.206 | 0.000 | – | 0.000 | – |
| Service branch: marine | 0.181 | 1.198 | 0.000 | – | 0.000 | – |
| Injury type: penetrating | 0.077 | 1.080 | 0.000 | – | 0.000 | – |
| AIS abdomen | 0.071 | 1.074 | 0.044 | 1.045 | 0.000 | – |
| First 24 hours transfusion: platelets | 0.034 | 1.035 | 0.000 | – | 0.064 | 1.066 |
| First 24 hours transfusion: whole blood | −0.027 | 0.973 | −0.021 | 0.979 | 0.000 | – |
| Days in ICU | 0.009 | 1.009 | 0.000 | – | 0.003 | 1.003 |
| Mechanism of injury: explosive | 0.005 | 1.005 | 0.000 | – | 0.000 | – |
| Days in hospital | 0.004 | 1.004 | 0.001 | 1.001 | 0.004 | 1.004 |
| Days on ventilator | 0.001 | 1.001 | 0.009 | 1.009 | 0.000 | – |
| AIS skin | 0.000 | – | 0.000 | – | 0.000 | – |
| First 24 hours transfusion: PRBC | 0.000 | – | 0.000 | – | 0.000 | – |
| First 24 hours transfusion: cryoprecipitate | 0.000 | – | 0.000 | – | 0.000 | – |
| First 24 hours transfusion: FFP | 0.000 | – | 0.000 | – | 0.000 | – |
| Estimated blood loss first 24 hours | 0.000 | – | 0.000 | – | 0.000 | – |
| Age | 0.000 | – | 0.004 | 1.004 | 0.000 | – |
| Injury year | 0.000 | – | 0.072 | 1.075 | 0.000 | – |
| Composite ISS | 0.000 | – | 0.000 | – | 0.000 | – |
| TXA1 | 0.000 | – | 0.000 | – | 0.000 | – |
| AIS head/neck | 0.000 | – | 0.000 | – | 0.000 | – |
| AIS face | 0.000 | – | 0.000 | – | 0.000 | – |
| AIS chest/thorax | 0.000 | – | 0.000 | – | 0.000 | – |
| AIS extremities | 0.000 | – | 0.111 | 1.117 | 0.000 | – |
| Service branch: army | 0.000 | – | 0.000 | – | −0.739 | 0.478 |
| Service branch: navy | 0.000 | – | −0.326 | 0.722 | 0.000 | – |
| Mechanism of injury: helicopter crash | 0.000 | – | −0.021 | 0.979 | 0.000 | – |
| Mechanism of injury: pedestrian | 0.000 | – | 0.000 | – | 0.000 | – |
| Injury type: blunt | 0.000 | – | 0.000 | – | 0.000 | – |
The variables are sorted by the magnitude of theparameter estimates for VTE.
FFP, fresh frozen plasma; GSW, gun shot wound; ICU, intensive care unit; ISS, injury severity score; MVC, motor vehicle crash; PRBC, packed red blood cell; TXA, tranexamic acid; VTE, venous thromboembolism.