Univariate analysis of the derivation cohort
| Variable | n | OR | 95% CI | P value |
| Traumatic brain injury | 705 | 11.52 | 7.04 to 18.83 | <0.001 |
| INR | 656 | 3.96 | 1.90 to 8.22 | <0.001 |
| Blunt injury | 705 | 2.46 | 1.59 to 3.80 | <0.001 |
| Creatinine (mg/dL) | 686 | 1.75 | 1.26 to 2.43 | 0.001 |
| PTT (s) | 657 | 1.14 | 1.10 to 1.18 | <0.001 |
| Age (years) | 707 | 1.03 | 1.02 to 1.04 | <0.001 |
| Systolic blood pressure (mm Hg) | 692 | 1.01 | 1.00 to 1.02 | 0.002 |
| Platelets (×103/µL) | 686 | 0.99 | 0.99 to 1.00 | <0.001 |
| Base excess (mmol/L) | 515 | 0.95 | 0.92 to 0.98 | 0.001 |
| Hemoglobin (g/dL) | 689 | 0.83 | 0.76 to 0.91 | <0.001 |
| Temperature (°C) | 489 | 0.43 | 0.33 to 0.57 | <0.001 |
↵PTT, partial thromboplastin time.